This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Because IMITREX Injection may increase blood pressure, it should not be given to patients with uncontrolled hypertension. A. Throw away the seal. Open the lid over the Syringe Cartridge. Drug Interactions: There is no evidence that concomitant use of migraine prophylactic medications has any effect on the efficacy of sumatriptan. Severe and sometimes fatal allergic reactions have rarely happened. Discuss any questions or concerns with your doctor.
Consult WARNINGS section for additional precautions. This drug may rarely cause serious possibly fatal disease. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bloody diarrhea; burning or aching in your feet or toes; burning, numbness, or tingling; constipation; diarrhea; fainting; feeling of heaviness or tightness in your leg muscles; fever; hearing problems; leg cramps; seizures; severe or persistent headache, dizziness, nausea, or vomiting; severe stomach pain; very cold or blue fingers or toes; vision changes or loss of vision; weight loss; wheezing.
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use and wear protective clothing when outdoors. You can take them as pills, injections, and skin patches. Your healthcare provider may change your dose. But these drugs can be habit-forming, so they should be used rarely and only for a short time.
Franceschini R, Cataldi A, Garibaldi A, Cianciosi P, Scordamaglia A, Barreca T, Rolandi E "The effects of sumatriptan on pituitary secretion in man. Preventive medicines often work when you take them at the first sign of a new cluster of headaches. Imitrex Injection is a prescription medicine used to treat acute migraine headaches with or without aura and acute cluster headaches in adults who have been diagnosed with migraine or cluster headaches. Sumatriptan can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medicine. Discontinue IMITREX Injection if these disturbances occur.
Dachs R, Vitillo J "Angioedema associated with sumatriptan administration. Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death, have been reported within a few hours following the administration of 5-HT 1 agonists. Discontinue Imitrex Tablets if these disturbances occur. Imitrex Tablets are contraindicated in patients with Wolff-Parkinson-White syndrome or arrhythmias associated with other cardiac accessory conduction pathway disorders. Imitrex is not for people with risk factors for heart disease unless a heart exam is done and shows no problem. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. It is best to use a dose of Imitrex spray as soon as you notice symptoms of a migraine attack.
NOTE: These photos can be used only for identification by shape, color, and imprint. They do not depict actual or relative size. Defects in the corneal epithelium were noted in a 60-week study. Earlier examinations for these toxicities were not conducted and no-effect doses were not established; however, the relative plasma exposure at the lowest dose tested was approximately 3 times the human exposure after a 6-mg subcutaneous dose. IMITREX Injection is intended to relieve your migraine or cluster headache, but not to prevent or reduce the number of attacks you experience. Use IMITREX Injection only to treat an actual migraine or cluster headache attack. If your symptoms do not improve after the first dose, do not use a second dose for the same attack. Contact your doctor. Clinical trials of Imitrex Injection did not include sufficient numbers of patients 65 years of age and older to determine whether they respond differently from younger patients. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. It is possible that some side effects of sumatriptan may not have been reported. Burning, tingling, dryness or pain in the nose nasal spray. This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. A different medication may be necessary in that case. Inject with the IMITREX STAT dose Pen. If you miss a dose of Imitrex spray and you still have a headache, follow your doctor's dosing instructions. Contact your doctor if you are unsure of what to do if you miss a dose. Do not use Imitrex spray more often than prescribed. Do not use 2 doses at once. Sumatriptan is excreted in human milk following subcutaneous administration. Infant exposure to sumatriptan can be minimized by avoiding breastfeeding for 12 hours after treatment with Imitrex Injection. Treatment should be started at the first sign of a migraine headache, or associated symptoms such as nausea, vomiting, or photophobia; this drug should not be used for migraine prophylaxis. clonidine
If you are taking chewable tablets, chew the tablet thoroughly before swallowing. If you miss a dose of Imitrex tablets and you still have a headache, follow your doctor's dosing instructions. Contact your doctor immediately if you are unsure of what to do if you miss a dose. Do not take Imitrex tablets more often than prescribed. Do not take 2 doses at once. This drug may make you dizzy or drowsy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Plasma exposure at the lowest dose tested was approximately 2 times that in humans at the MRHD. Are the headaches triggered by something in your environment, such as smells, noise, or some kinds of weather? Sumatriptan can pass into breast milk and may harm a nursing baby. Do not breast-feed within 12 hours after using a sumatriptan injection. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Product Information. Zecuity SUMAtriptan. Boyd IW, Rohan AP "Sumatriptan-induced chest pain. Urogenital: Rare were dysuria, frequency, dysmenorrhea, and renal calculus. Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions, including: high blood pressure, high cholesterol, diabetes, family history of heart disease, overweight, smoker, postmenopausal women age more than 40 years men. What are the possible side effects of IMITREX? Gastrointestinal: Infrequent were gastroesophageal reflux, diarrhea, and disturbances of liver function tests. Neither of these adverse events was associated with a serious clinical outcome. If your migraine symptoms go away and then come back, you may use a second dose as directed by your doctor. Wait at least 2 hours between doses. You may have to try different drugs or doses. If you have already tried several medicines, your doctor may order tests such as an or to find out if a health problem is causing your headaches. Consult your doctor or if you have questions about the ingredients in your brand. topamax buy online shopping uk topamax
Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to quickly treat any serious side effects that occur. Other Vasospasm-Related Events: Sumatriptan may cause vasospastic reactions other than coronary artery vasospasm. Both peripheral vascular ischemia and colonic ischemia with abdominal pain and bloody diarrhea have been reported. Very rare reports of transient and permanent blindness and significant partial vision loss have been reported with the use of sumatriptan. Visual disorders may also be part of a migraine attack. Sumatriptan is excreted in human milk following subcutaneous administration. Use of this medicine for 10 or more days per month may exacerbate headaches; use a headache diary to record how often you have a headache and when you take this medicine. Safety and effectiveness in pediatric patients have not been established. Imitrex Tablets are not recommended for use in patients younger than 18 years of age.
Urogenital: Abnormal menstrual cycle, abortion, bladder inflammation, endometriosis, hematuria, increased urination, inflammation of fallopian tubes, intermenstrual bleeding, menstruation symptoms, micturition disorders, urethritis, and urinary infections. IMITREX STATdose Pen, 2 prefilled single-dose syringe cartridges, and 1 carrying case NDC 0173-0739-00. Important: The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, blogs, or WebMD Answers are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Imitrex Nasal Spray sumatriptan Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container ask your pharmacist where to get one and how to throw it away. Keep this container out of the reach of children and pets. The plot was constructed with data from patients who either experienced relief or did not require request rescue medication within a period of 2 hours following treatment. As a consequence, the data in the plot are derived from only a subset of the 258 headaches treated rescue medication was required in 52 of the 127 placebo-treated headaches and 18 of the 131 headaches treated with Imitrex Injection. IMITREX Injection should not be given intravenously because of its potential to cause coronary vasospasm. They work great if you have about four headaches per month, but for people with more you need a triptan. Imitrex is great for about two headaches per week, but anymore than that and you risk being like me. I am resistant to about everything. IMITREX STATdose System NDC 0173-0739-02. Plot also includes patients who had no response to the initial dose. Triptans narrow constrict vessels in the and relieve swelling. Triptans have other properties that may help treat symptoms. IMITREX. Such reactions can be life threatening or fatal. Autoinjector Pen: Each pack contains a Patient Information and Instructions for Use leaflet. Do not stop taking any medications without consulting your healthcare provider. You can buy some over the counter. But stronger NSAIDs need a prescription. gabbe.info florinef
You can take it as a pill or as a suppository if nausea or vomiting stops you from keeping anything down. Another form of ergotamine, called DHE 45 also treats them. You can get it as an injection or as a nasal spray. Serious cardiac events, including some that have been fatal, have occurred following the use of IMITREX Injection or Tablets. These events are extremely rare and most have been reported in patients with risk factors predictive of CAD. Number of headaches treated. Product Information. Imitrex nasal spray sumatriptan. Do not start, stop, or change the dosage of any medicines without your doctor's approval. They are usually triggered after pain medicine has worn off, prompting you to take another dose. Eventually you get a headache whenever you stop taking the drug. Be sure to take your migraine medicine only as prescribed by your doctor. Side Effects List Sumatriptan-Naproxen Tablet side effects by likelihood and severity. Pen and the Cartridge Pack when they are not being used. The product samples shown here have been supplied by the manufacturer. While every effort has been made to assure accurate reproduction, please remember that any visual identification should be considered preliminary. In cases of poisoning or suspected overdosage, the drug's identity should be verified by chemical analysis. The pain is almost always one-sided, and it stays on the same side during a period, the time when you're getting daily attacks. When a new headache period starts, it might switch to the opposite side, but that's rare. Imitrex Injection also relieved photophobia, phonophobia sound sensitivity nausea, and vomiting associated with migraine attacks. Similar efficacy was seen when patients self-administered Imitrex Injection using the IMITREX STATdose Pen. Your healthcare provider may change your dose. Do not change your dose without first talking to your healthcare provider. Contact your doctor if you have more than four headaches in one month 30 days. Tell your doctor if this medicine seems to stop working as well in treating your migraine attacks. Injection: 4-mg and 6-mg single-dose prefilled syringe cartridges for use with the IMITREX STATdose Pen. IMITREX is not for people with risk factors for heart disease unless a heart exam is done and shows no problem. Who should not take IMITREX? can you asacol in usa
Sumatriptan belongs to a group of drugs called triptans. Sumatriptan is used to treat migraines. How often do you have them? You may experience pain or redness at the site of injection, but this usually lasts less than an hour. Drowsiness may occur during a migraine or during its treatment with this drug. Do not drive or operate machinery until you know how this drug affects you. Heart Rate: Transient increases in blood pressure observed in some patients in clinical studies carried out during sumatriptan's development as a treatment for migraine were not accompanied by any clinically significant changes in heart rate. If there is no improvement in your symptoms, not take any more doses of this medication before talking to your doctor. If your symptoms are only partly relieved, or if your comes back, you may use a second injection after one hour or as directed by your doctor. Do not use more than 12 milligrams in a 24-hour period. Do not reuse the syringe or the needle-free device. If you are using an auto-injector device, it may be re-used. Imitrex Tablets. Such reactions can be life threatening or fatal. Sumatriptan may also be used for purposes not listed in this medication guide. AUC corresponding to a 40% increase in elimination half-life. Fast or slow heartbeat. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure. Store at room temperature away from moisture, heat, and light. Throw away any unused medicine after the expiration date on the label has passed. What happens if I miss a dose? Read the Guide provided by your before you start using this product and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Vagus nerve, since the headaches are immediately connected to the urge to have a bowel movement. When did your headaches first start? Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because these effects may be additive, use of ergotamine-containing or ergot-type medications like dihydroergotamine or methysergide and Imitrex Injection within 24 hours of each other is contraindicated. Silberstein SD, et al. 2012. Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults: Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Neurology, 7817: 1337-1345. It may harm them. Medication overuse headache may present as migraine-like daily headaches or as a marked increase in frequency of migraine attacks. Detoxification of patients, including withdrawal of the overused drugs, and treatment of withdrawal symptoms which often includes a transient worsening of headache may be necessary. Imitrex Injection should continue for at least 10 hours or while symptoms or signs persist. You are using medicines to stop headaches more than 3 times a week. Since the injection is intended to be given subcutaneously, intramuscular or intravascular delivery should be avoided. Patients should be directed to use injection sites with an adequate skin and subcutaneous thickness to accommodate the length of the needle. Seizures have been reported following administration of Imitrex. Some have occurred in patients with either a history of seizures or concurrent conditions predisposing to seizures. There are also reports in patients where no such predisposing factors are apparent. Imitrex Tablets should be used with caution in patients with a history of epilepsy or conditions associated with a lowered seizure threshold. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. Other News "AAN meeting: sumatriptan linked to life-threatening intestinal condition. You may begin to sweat a lot, or light may bother you. Prompt treatment allows you to get back to your normal routine and may decrease your need for other pain medications. If any of these effects persist or worsen, tell your doctor or promptly. cheap cyproheptadine order payment usa
If you use too much IMITREX, call your healthcare provider or go to the nearest hospital emergency room right away. IMITREX and AMERGE are registered trademarks of the GSK group of companies. The other brands listed are trademarks of their respective owners and are not trademarks of the GSK group of companies. The makers of these brands are not affiliated with and do not endorse the GSK group of companies or its products. Try these drugs first. Cluster headaches generally reach their full force quickly -- within 5 or 10 minutes. This does not prevent future or lessen how often you get attacks. The osmolality of the injection is 291 mOsmol. System out of the reach of children. Use calendars and clocks. Nov. 7, 2003 -- The success or failure of treatment with the most commonly prescribed may depend on timing. If some response to first dose occurs, a second dose may be administered at least 1 hour after first dose if needed. buy allopurinol pills
Take the Pen out of the Carrying Case. If concomitant treatment with sumatriptan and an SSRI is clinically warranted, appropriate observation of the patient is advised. MAO-A inhibitor on the bioavailability from a 25-mg oral sumatriptan tablet resulted in an approximately 7-fold increase in systemic exposure. Schoenen J, Bulcke J, Caekebeke J, Dehaene I, Dekeyser J, Hildebrand G, Joffroy A, Laloux P, Louis P, Monseu G, Pierre P, Vander "Self-treatment of acute migraine with subcutaneous sumatriptan using an auto-injector device - comparison with customary treatment in an open, longitudinal study. How should I use sumatriptan? Overuse of drugs to treat sudden migraine attacks can sometimes lead to worsening of headache medication overuse headache or rebound headache. Therefore, do not use this medication more often or for longer than prescribed. Tell your doctor if you need to use this medication more often, if the medication is not working as well, or if you have more frequent or worse headaches. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs. Nasal spray: A 10 mg intranasal dose may be administered as 5 mg in each nostril. Anti-nausea medications. These drugs may help you absorb your pain medication. Before you use any treatment for a memory problem, discuss the potential risks and benefits of the treatment with your doctor. ZecuityR was voluntarily withdrawn from the market by the manufacturer in June 2016 due to reports of serious application site reactions associated with use of this iontophoretic transdermal system. Since marketing of the patch in September 2015, there have been a number of reports in which patients describe severe redness, cracked skin, blistering or welts, and burns or scars where the patch was worn. Many report resolution within hours to weeks, although there are reports of unresolved skin reactions, typically skin discoloration. Severe or pressure or a strange feeling in the chest. Some people feel pain, pressure, or a strange feeling in the back, neck, jaw, or upper belly, or in one or both shoulders or arms. These medicines can help prevent headaches even if you don't have or seizures. IMITREX Injection is a clear, colorless to pale yellow, sterile, nonpyrogenic solution for subcutaneous injection.
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These reports include events similar in nature to those reported rarely in adults, including stroke, visual loss, and death. A myocardial infarction has been reported in a 14-year-old male following the use of oral sumatriptan; clinical signs occurred within 1 day of drug administration. Since clinical data to determine the frequency of serious adverse events in pediatric patients who might receive injectable, oral, or intranasal sumatriptan are not presently available, the use of sumatriptan in patients aged younger than 18 years is not recommended. Are you taking any other migraine medicines, including other 5-HT 1 agonists or any other medicines containing ergotamine, dihydroergotamine, or methysergide? bicalutamide
Imitrex. Such reactions can be life threatening or fatal. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens. Imitrex Tablets are contraindicated in patients with a history of hypersensitivity reaction to Imitrex. Open the Carrying Case lid. Discontinue IMITREX Injection if a cerebrovascular event occurs. Injection: 6-mg single-dose vial.
USP in water for injection, USP. IMITREX Injection is contraindicated. Feeling hot or cold, weak, or "strange" in some way. HGPRT assay. In 2 cytogenetics assays the in vitro human lymphocyte assay and the in vivo rat micronucleus assay sumatriptan was not associated with clastogenic activity.
Do you have any chest pain, heart disease, shortness of breath, or irregular heartbeats? PREGNANCY and BREAST-FEEDING: It is not known if Imitrex tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imitrex tablets while you are pregnant. Imitrex tablets are found in breast milk. If you are or will be breast-feeding while you use Imitrex tablets, check with your doctor. Discuss any possible risks to your baby. The trials did not establish the efficacy of Imitrex Nasal Spray compared with placebo in the treatment of migraine in adolescents. Adverse reactions observed in these clinical trials were similar in nature to those reported in clinical trials in adults.